Bivalent mRNA booster encoding virus-like particles elicits potent polyclass receptor-binding domain antibodies in pre-vaccinated mice

mRNA vaccines emerged as a leading vaccine technology during the COVID-19 pandemic. However, their sustained protective efficacies were limited by relatively short-lived antibody responses and the emergence of SARS-CoV-2 variants, necessitating frequent and variant-updated boosters. We recently deve...

وصف كامل

التفاصيل البيبلوغرافية

المؤلفون الرئيسيون:	Chengcheng Fan, Alexander A Cohen, Kim-Marie A Dam, Annie V Rorick, Ange-Célia I Priso Fils, Zhi Yang, Priyanthi NP Gnanapragasam, Luisa N Segovia, Kathryn E Huey-Tubman, Woohyun J Moon, Paulo JC Lin, Pamela J Bjorkman, Magnus AG Hoffmann
التنسيق:	Artigo
اللغة:	Inglês
منشور في:	eLife Sciences Publications Ltd 2026-04-01
سلاسل:	eLife
الموضوعات:	mRNA vaccines SARS-CoV-2 epitope targeting immune imprinting
الوصول للمادة أونلاين:	https://elifesciences.org/articles/108959
الوسوم:	إضافة وسم لا توجد وسوم, كن أول من يضع وسما على هذه التسجيلة!