Monitoring β-arrestin recruitment via β-lactamase enzyme fragment complementation: purification of peptide E as a low-affinity ligand for mammalian bombesin receptors.

Identification of cognate ligands for G protein-coupled receptors (GPCRs) provides a starting point for understanding novel regulatory mechanisms. Although GPCR ligands have typically been evaluated through the activation of heterotrimeric G proteins, recent studies have shown that GPCRs signal not...

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Autori principali:	Yuichi Ikeda, Hidetoshi Kumagai, Hiroaki Okazaki, Mitsuhiro Fujishiro, Yoshihiro Motozawa, Seitaro Nomura, Norifumi Takeda, Haruhiro Toko, Eiki Takimoto, Hiroshi Akazawa, Hiroyuki Morita, Jun-ichi Suzuki, Tsutomu Yamazaki, Issei Komuro, Masashi Yanagisawa
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Public Library of Science (PLoS) 2015-01-01
Serie:	PLoS ONE
Accesso online:	http://europepmc.org/articles/PMC4452343?pdf=render
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