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Dual pH- and Thermo-Sensitive Poly(N-isopropylacrylamide-co-allylamine) Nanogels for Curcumin Delivery: Swelling–Deswelling Behavior and Phase Transition Mechanism

Curcumin (Cur) is a beneficial ingredient with numerous bioactivities. However, due to its low solubility and poor bioavailability, its therapeutic application is limited. In this work, we prepared poly-N-isopropylacrylamide p(NIPAm) and polyallylamine p(Am)-based nanogel (p(NIPAm-co-Am)) NG for a d...

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Principais autores: Madhappan Santhamoorthy, Seong-Cheol Kim
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2023-07-01
Serier:Gels
Fag:
pNIPAm copolymer
dual stimuli
drug delivery
phase transition
cytocompatibility
Online adgang:https://www.mdpi.com/2310-2861/9/7/536
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