3D QSAR, pharmacophore indentification studies on series of 1-(2-ethoxyethyl)-1H-pyrazolo [4,3-d]pyrimidines as phosphodiesterase V inhibitors

Context: In recent years phosphodiesterase V acts as an attractive target for cardiovascular drug design and QSAR techniques are helpful for the optimization of structural requirements for designing novel compounds. Objective: The present communication deals with 3D-QSAR analysis of 1-(2-ethoxyethyl...

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Hlavní autoři:	Prafulla Choudhari, Manish Bhatia
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Springer 2015-05-01
Edice:	Journal of Saudi Chemical Society
Témata:	Molecular modeling k-Nearest neighbor molecular field analysis (kNN-MFA Multiple linear regression analysis Vlife MDS 3.5 Phosphodiesterase 5 Vascular smooth muscle relaxant 3D QSAR
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S1319610312000403
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