QR-Code

Influence of Genetic Polymorphisms on the Age at Cancer Diagnosis in a Homogenous Lynch Syndrome Cohort of Individuals Carrying the <i>MLH1</i>:c.1528C>T South African Founder Variant

<b>Background:</b> High variability in the age at cancer diagnosis in Lynch syndrome (LS) patients is widely observed, even among relatives with the same germline pathogenic variant (PV) in the mismatch repair (MMR) genes. Genetic polymorphisms and lifestyle factors are thought to contribute to this...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Lutricia Ndou, Ramadhani Chambuso, Ursula Algar, Paul Goldberg, Adam Boutall, Raj Ramesar
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2024-09-01
Schriftenreihe:Biomedicines
Schlagworte:
Lynch syndrome
age at cancer diagnosis
colorectal cancer
Lynch syndrome-associated cancer
extracolonic cancer
genetic polymorphisms
Online-Zugang:https://www.mdpi.com/2227-9059/12/10/2201
Tags: Tag hinzufügen
Keine Tags, Fügen Sie das erste Tag hinzu!

Ähnliche Einträge