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MerTK inhibitor suppresses melanoma growth in mice by regulating the quantity and phenotype of tumor-associated macrophages

[Objective] To investigate the effect of the MerTK inhibitor UNC2250 on tumor growth in melanoma mice and to preliminarily elucidate its mechanism of action. [Methods] Sixteen healthy C57BL/6 mice were randomly divided into a control group and low-, medium-, and high-dose UNC2250 treatment groups, w...

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Autori principali: WU Naming, SHA Shanshan, YANG Liu
Natura: Artigo
Lingua:Chinês
Pubblicazione: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology 2025-07-01
Serie:Pifu-xingbing zhenliaoxue zazhi
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Accesso online:http://pfxbzlx.gdvdc.com/EN/10.3969/j.issn.1674-8468.2025.07.001
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