Immunization with Live Attenuated Leishmania donovani Centrin−/− Parasites Is Efficacious in Asymptomatic Infection

Currently, there is no vaccine against visceral leishmaniasis (VL). Toward developing an effective vaccine, we have reported extensively on the immunogenicity of live attenuated LdCentrin−/− mutants in naive animal models. In VL endemic areas, asymptomatic carriers outnumber symptomatic cases of VL...

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Bibliographic Details

Main Authors:	Nevien Ismail, Amit Kaul, Parna Bhattacharya, Sreenivas Gannavaram, Hira L. Nakhasi
Format:	Artigo
Language:	Inglês
Published:	Frontiers Media S.A. 2017-12-01
Series:	Frontiers in Immunology
Subjects:	asymptomatic infections live attenuated vaccines Leishmania donovani biomarkers of protection immunogenicity
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2017.01788/full
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