Structural and biochemical basis of methylmalonate semialdehyde dehydrogenase ALDH6A1

Background: ALDH6A1, a member of the ALDH family, plays a crucial role in the catabolic pathways of valine and thymine. Dysregulation of ALDH6A1 expression has been linked to a variety of diseases. Methylmalonate semialdehyde dehydrogenase deficiency (MMSDH deficiency), an autosomal recessive disord...

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Hlavní autoři:	Gengchen Su, Kaide Ju, Youwei Xu, Ye Jin, Limeng Chen, Shuyang Zhang, Xiaodong Luan
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	KeAi Communications Co., Ltd. 2024-03-01
Edice:	Medicine Plus
Témata:	ALDH6A1 Aldehyde dehydrogenase Alda-1 Enzyme activity
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2950347724000045
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