Incorporating functional annotation with bilevel continuous shrinkage for polygenic risk prediction
Abstract Background Genetic variants can contribute differently to trait heritability by their functional categories, and recent studies have shown that incorporating functional annotation can improve the predictive performance of polygenic risk scores (PRSs). In addition, when only a small proporti...
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| Asıl Yazarlar: | , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
BMC
2024-02-01
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| Seri Bilgileri: | BMC Bioinformatics |
| Konular: | |
| Online Erişim: | https://doi.org/10.1186/s12859-024-05664-2 |
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