Mechanistic Models of Protein Aggregation Across Length-Scales and Time-Scales: From the Test Tube to Neurodegenerative Disease

Through advances in the past decades, the central role of aberrant protein aggregation has been established in many neurodegenerative diseases. Crucially, however, the molecular mechanisms that underlie aggregate proliferation in the brains of affected individuals are still only poorly understood. U...

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Egile Nagusiak:	Georg Meisl, Tuomas P. J. Knowles, David Klenerman
Formatua:	Artigo
Hizkuntza:	Inglês
Argitaratua:	Frontiers Media S.A. 2022-06-01
Saila:	Frontiers in Neuroscience
Gaiak:	neurodegenerative disease chemical kinetics mechanistic models protein aggregation in vivo models amyloid
Sarrera elektronikoa:	https://www.frontiersin.org/articles/10.3389/fnins.2022.909861/full
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