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DNA microarray profiling of genes differentially regulated by the histone deacetylase inhibitors vorinostat and LBH589 in colon cancer cell lines

<p>Abstract</p> <p>Background</p> <p>Despite the significant progress made in colon cancer chemotherapy, advanced disease remains largely incurable and novel efficacious chemotherapies are urgently needed. Histone deacetylase inhibitors (HDACi) represent a novel class of agents which have demonstrat...

Бүрэн тодорхойлолт

-д хадгалсан:
Номзүйн дэлгэрэнгүй
Үндсэн зохиолчид: Lenz Heinz-Josef, Groshen Susan, Fazzone William, Wilson Peter M, LaBonte Melissa J, Ladner Robert D
Формат: Artigo
Хэл сонгох:Inglês
Хэвлэсэн: BMC 2009-11-01
Цуврал:BMC Medical Genomics
Онлайн хандалт:http://www.biomedcentral.com/1755-8794/2/67
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