Tunicamycin Induces Hepatic Stellate Cell Apoptosis Through Calpain-2/Ca2 +-Dependent Endoplasmic Reticulum Stress Pathway

It has been reported that calpain/caspase-mediated apoptosis induced by endoplasmic reticulum stress (ERS) in hepatic stellate cells (HSCs) by previous studies. At present, the activation of HSC is an important cause of liver fibrosis, and the induction of HSC apoptosis plays an irreplaceable role i...

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Principais autores:	Haiying Liu, Linyu Dai, Ming Wang, Fumin Feng, Yonghong Xiao
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Frontiers Media S.A. 2021-09-01
coleção:	Frontiers in Cell and Developmental Biology
Assuntos:	tunicamycin calpain-2 apoptosis endoplasmic reticulum stress hepatic stellate cells
Acesso em linha:	https://www.frontiersin.org/articles/10.3389/fcell.2021.684857/full
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