SREBP1 induction mediates long-term statins therapy related myocardial lipid peroxidation and lipid deposition in TIIDM mice

Statins therapy is efficacious in diminishing the risk of major cardiovascular events in diabetic patients. However, our research has uncovered a correlation between the prolonged administration of statins and an elevated risk of myocardial dysfunction in patients with type II diabetes mellitus (TII...

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Hlavní autoři:	Tong-sheng Huang, Teng Wu, Xin-lu Fu, Hong-lin Ren, Xiao-dan He, Ding-hao Zheng, Jing Tan, Cong-hui Shen, Shi-jie Xiong, Jiang Qian, Yan Zou, Jun-hong Wan, Yuan-jun Ji, Meng-ying Liu, Yan-di Wu, Xing-hui Li, Hui Li, Kai Zheng, Xiao-feng Yang, Hong Wang, Meng Ren, Wei-bin Cai
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Elsevier 2024-12-01
Edice:	Redox Biology
Témata:	Statins Sterol regulatory element-binding protein 1 Type 2 diabetes mellitus Myocardial lipid peroxidation
On-line přístup:	http://www.sciencedirect.com/science/article/pii/S2213231724003902
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