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FcγRIIIa receptor polymorphism influences NK cell mediated ADCC activity against HIV

Abstract Background HIV-specific Antibody Dependent Cell Cytotoxicity (ADCC) has shown to be important in HIV control and resistance. The ADCC is mediated primarily by natural killer cell activated through the binding of FcγRIIIa receptor to the Fc portion of antibody bound to the antigen expressed...

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Autori principali: Sneha Pramod Talathi, Nawaj Najir Shaikh, Sudhanshu Shekhar Pandey, Vandana Ashish Saxena, Megha Sunil Mamulwar, Madhuri Rajeev Thakar
Natura: Artigo
Lingua:Inglês
Pubblicazione: BMC 2019-12-01
Serie:BMC Infectious Diseases
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Accesso online:https://doi.org/10.1186/s12879-019-4674-z
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