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RARRES1 inhibits hepatocellular carcinoma progression and increases its sensitivity to lenvatinib through interaction with SPINK2

Abstract Background Lenvatinib is an oral small molecule inhibitor approved for treating patients with unresectable hepatocellular carcinoma (HCC) worldwide. Increasing cell sensitivity to lenvatinib would be an effective method of improving therapeutic efficacy. Methods High throughput methods was...

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Principais autores: Yarong Guo, Bao Chai, Hezhao Zhang, Xinhao Chai, Yan Chen, Jun Xu, Liwei Qin, Yuting Chai
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2024-02-01
coleção:Biology Direct
Assuntos:
Lenvatinib
RARRES1
SPINK2
Sensitivity
Acesso em linha:https://doi.org/10.1186/s13062-024-00459-0
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