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LytB1 and LytB2 of Mycobacterium tuberculosis Are Not Genetically Redundant.

Mycobacterium tuberculosis synthesises isoprenoid precursors via the MEP/DOXP pathway and at least five enzymes in the pathway (Dxs1, Dxr/IspC, IspD, IspF, and GcpE/IspG) are required for growth in vitro. We investigated the role of LytB (IspH) in M. tuberculosis; M. tuberculosis is unusual in that...

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Bibliografske podrobnosti
Principais autores: Amanda Claire Brown, Rachel Kokoczka, Tanya Parish
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2015-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC4550268?pdf=render
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