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Enantio-, atrop-, and diastereoselective macrolactonization to access type III cyclophanes

Abstract Although chiral substituents have been incorporated into ansa chains to stabilize the conformations of cyclophanes and modulate the biological activities of pharmaceuticals, the asymmetric syntheses of these atropisomers relies on substrate-induced diastereoselective macrocyclization. To th...

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Bibliografiset tiedot
Päätekijät: Jiaming Wang, Kang Lv, Yilu Wen, Tao Liu, Changgui Zhao
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2025-04-01
Sarja:Nature Communications
Linkit:https://doi.org/10.1038/s41467-025-58241-3
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