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Mechanism of YAP1 in the senescence and degeneration of endplate chondrocytes induced by intermittent cyclic mechanical tension

Abstract Background This study aimed to investigate the potential mechanism of YAP1 in the senescence and degeneration of endplate chondrocytes induced by intermittent cyclic mechanical tension (ICMT). Methods According to the Pfirrmann grade evaluation classification, 30 human endplate cartilage ti...

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Principais autores: Lei Kong, Yong-Sheng Xie, Xu-Dong Ma, Yan Huang, Xi-Fu Shang
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2023-03-01
Serier:Journal of Orthopaedic Surgery and Research
Fag:
Endplate cartilage
Degenerative
Senescence
YAP1
ICMT
Online adgang:https://doi.org/10.1186/s13018-023-03704-w
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