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Predictive modeling of controlled drug release from polysaccharide-based systems using gradient boosting and metaheuristic optimization

Abstract Accurate prediction of drug release kinetics from polysaccharide-based delivery systems is essential for rational formulation design. In this study, a hybrid machine learning framework integrating Raman spectroscopy with formulation descriptors is developed to model drug release profiles ac...

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Autori principali: Ahmed H. Albariqi, Abdullah Alsalhi, Meshal Alshamrani, Sameer Alshehri, Mahboubeh Pishnamazi
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2026-04-01
Serie:Scientific Reports
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Accesso online:https://doi.org/10.1038/s41598-026-48281-0
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