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Clinical, Genetic, and Prognostic Features of Adrenocortical Tumors in Children: A 10-Year Single-Center Experience

Background and Aims: Pediatric adrenocortical tumors (ACTs) are very rare endocrine neoplasms in childhood. In this study, we performed a retrospective analysis of children with ACT treated at our institution by examining clinical and genetic disease features, treatment strategies, and outcomes.Meth...

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Principais autores: Evelina Miele, Angela Di Giannatale, Alessandro Crocoli, Raffaele Cozza, Annalisa Serra, Aurora Castellano, Antonella Cacchione, Maria Giuseppina Cefalo, Rita Alaggio, Maria Debora De Pasquale
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2020-10-01
Serija:Frontiers in Oncology
Teme:
adrenocortical tumors
children
Li-Fraumeni Syndrome
Beckwith–Wiedeman syndrome
mitotane
immunotherapy
Online dostop:https://www.frontiersin.org/article/10.3389/fonc.2020.554388/full
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