Subcellular distribution of ERK phosphorylation in tyrosine and threonine depends on redox status in murine lung cells.
Activation of ERK1/2 implies the phosphorylation of tyrosine (pTyr) and threonine (pThr) by MEK1/2; both reactions were thought to be cytoplasmic, promoting ERK to reach the nucleus where it activates several transcription factors. In addition, H2O2 concentrations are known to modulate ERK intracell...
Guardat en:
| Autors principals: | , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science (PLoS)
2018-01-01
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| Col·lecció: | PLoS ONE |
| Accés en línia: | http://europepmc.org/articles/PMC5831038?pdf=render |
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