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Metabolomics identifies disturbances in arginine, phenylalanine, and glycine metabolism as differentiating features of exacerbating atopic asthma in children

Background: Asthma exacerbations are highly prevalent in children, but only a few studies have examined the biologic mechanisms underlying exacerbations in this population. Objective: High-resolution metabolomics analyses were performed to understand the differences in metabolites in children with e...

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Principais autores: Kirsten A. Cottrill, PhD, Joshua D. Chandler, PhD, Seibi Kobara, PT, MPH, Susan T. Stephenson, PhD, Ahmad F. Mohammad, BS, Mallory Tidwell, BSN, RN, Carrie Mason, BS, RRT, Morgan Van Dresser, RN, MSN, James Patrignani, BS, Rishikesan Kamaleswaran, PhD, Anne M. Fitzpatrick, PhD, Jocelyn R. Grunwell, MD, PhD
פורמט: Artigo
שפה:Inglês
יצא לאור: Elsevier 2023-08-01
סדרה:Journal of Allergy and Clinical Immunology: Global
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גישה מקוונת:http://www.sciencedirect.com/science/article/pii/S2772829323000401
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