UCseek: ultrasensitive early detection and recurrence monitoring of urothelial carcinoma by shallow-depth genome-wide bisulfite sequencing of urinary sediment DNAResearch in context

Summary: Background: Current methods for the detection and surveillance of urothelial carcinomas (UCs) are often invasive, costly, and not effective for low-grade, early-stage, and minimal residual disease (MRD) tumors. We aimed to develop and validate a model from urine sediments to predict differ...

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Bibliografische Detailangaben

Hauptverfasser:	Ping Wang, Yue Shi, Jianye Zhang, Jianzhong Shou, Mingxin Zhang, Daojia Zou, Yuan Liang, Juan Li, Yezhen Tan, Mei Zhang, Xingang Bi, Liqun Zhou, Weimin Ci, Xuesong Li
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2023-03-01
Schriftenreihe:	EBioMedicine
Schlagworte:	Urothelial carcinoma Molecular diagnostics Tumor markers Diagnosis Relapse monitoring Machine learning
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S2352396423000026
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