Xuesanqi ameliorates DSS-induced colitis in mice by mediating gut microbiota dysbiosis and modulating MAPK/ERK/JNK pathway

Abstract This study aimed to evaluate the therapeutic properties of the traditional Chinese medicine Xuesanqi (XSQ, from the rhizome of Polygonum amplexicaule D. Don) in treating ulcerative colitis. We hypothesized that its many active components can alleviate symptoms of colitis by regulating the g...

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Autors principals:	Qiyuan Su, Qian Hu, Songtao Wu, Suqin Yang, Hanwen Su, Zhengjun Zhang, Chengxiu Ling
Format:	Artigo
Idioma:	Inglês
Publicat:	SpringerOpen 2024-12-01
Col·lecció:	Natural Products and Bioprospecting
Matèries:	Colitis Xuesanqi Gut microbiota Short chain fatty acids (SCFas) MAPK/ERK/JNK signaling pathway Tight junction (T.J.) protein
Accés en línia:	https://doi.org/10.1007/s13659-024-00482-8
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