Risk factors for human papillomavirus infection, cervical intraepithelial neoplasia and cervical cancer: an umbrella review and follow-up Mendelian randomisation studies

Abstract Background Persistent infection by oncogenic human papillomavirus (HPV) is necessary although not sufficient for development of cervical cancer. Behavioural, environmental, or comorbid exposures may promote or protect against malignant transformation. Randomised evidence is limited and the...

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Hauptverfasser:	Sarah J. Bowden, Triada Doulgeraki, Emmanouil Bouras, Georgios Markozannes, Antonios Athanasiou, Harriet Grout-Smith, Konstantinos S. Kechagias, Laura Burney Ellis, Verena Zuber, Marc Chadeau-Hyam, James M. Flanagan, Konstantinos K. Tsilidis, Ilkka Kalliala, Maria Kyrgiou
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	BMC 2023-07-01
Schriftenreihe:	BMC Medicine
Schlagworte:	HPV Cervical cancer Cervical intraepithelial neoplasia CIN Umbrella Mendelian randomisation
Online-Zugang:	https://doi.org/10.1186/s12916-023-02965-w
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