Thyroid hormone resistance syndrome caused by a novel mutation in the thyroid hormone receptor‐beta gene (THRB, GLU457LYS) treated with methimazole

Abstract A 15‐year‐old girl presented with hyperactivity and behavior disorders. She had tachycardia and no goiter. Thyroid hormones were high and TSH normal. A novel mutation GLU457LYS in THRB gene was observed. Methimazole and propranolol improved clinical symptoms but increased TSH level.

Detalles Bibliográficos

Principais autores:	Imen Rezgani, Melika Chihaoui, Ibtissem Oueslati, Fatma Chaker, Sonia Nagi, Meriem Yazidi
Formato:	Artigo
Idioma:	Inglês
Publicado:	Wiley 2022-11-01
Series:	Clinical Case Reports
Assuntos:	anti‐thyroid drug hyperthyroidism THRB, GLU457LYS thyroid hormone receptor gene thyroid hormone resistance
Acceso en liña:	https://doi.org/10.1002/ccr3.6543
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