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Integrin α6β4 Confers Doxorubicin Resistance in Cancer Cells by Suppressing Caspase-3–Mediated Apoptosis: Involvement of N-Glycans on β4 Integrin Subunit

Drug resistance is a major obstacle to successful cancer treatment. Therefore, it is essential to understand the molecular mechanisms underlying drug resistance to develop successful therapeutic strategies. α6β4 integrin confers resistance to apoptosis and regulates the survival of cancer cells; how...

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Hlavní autoři: Yoshinobu Kariya, Jianguo Gu, Yukiko Kariya
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2023-12-01
Edice:Biomolecules
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On-line přístup:https://www.mdpi.com/2218-273X/13/12/1752
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