Generation of Nonhuman Primate Model of Cone Dysfunction through In Situ AAV-Mediated CNGB3 Ablation

Summary: A major challenge to the development of therapies for human retinal degenerative diseases is the lack of an ideal preclinical model because of the physiological differences between humans and most model animals. Despite the successful generation of a primate model through germline knockout...

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Hauptverfasser:	Qiang Lin, Ji-Neng Lv, Kun-Chao Wu, Chang-Jun Zhang, Qin Liu, Zi-Bing Jin
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Elsevier 2020-09-01
Schriftenreihe:	Molecular Therapy: Methods & Clinical Development
Online-Zugang:	http://www.sciencedirect.com/science/article/pii/S232905012030173X
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