Determination of lamotrigine in human plasma using liquid chromatography‐tandem mass spectrometry

Abstract Aim Lamotrigine (LTG) is a widely used anti‐epileptic drug that is administered to avoid seizures and to maintain seizure‐free status. However, several factors reportedly cause individual differences of plasma LTG levels, and the therapeutic target range of LTG varies between individuals. T...

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Hauptverfasser:	Shogo Itabashi, Rina Bito, Maika Nishina, Maki Fukumoto, Midori Soda, Mitsunori Doi, Shigeyuki Usui, Kiyoyuki Kitaichi
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Wiley 2019-03-01
Schriftenreihe:	Neuropsychopharmacology Reports
Schlagworte:	epilepsy lamotrigine liquid chromatography‐tandem mass spectrometry plasma concentration solid‐phase extraction
Online-Zugang:	https://doi.org/10.1002/npr2.12045
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