Extracellular vesicles cargo orchestration in colorectal cancer: immune evasion, stromal remodeling, and therapeutic frontiers

Abstract Extracellular vesicles (EVs), as pivotal “messengers” in intercellular communication within the tumor microenvironment (TME), play multifaceted regulatory roles in the initiation, progression, and therapeutic response of colorectal cancer (CRC). This review focuses on the roles of EVs in CR...

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Hlavní autoři:	Yukang Lu, Xiulan Liu, Tingting Zhang, Meijin Liu, Xiaoyan Liu, Jinyou Qiu, Linghan Zhang, Zhenzhen Wen
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	BMC 2025-12-01
Edice:	Molecular Cancer
Témata:	Extracellular vesicles Colorectal cancer Tumor microenvironment Immunosuppression Therapeutic strategies Engineered extracellular vesicles
On-line přístup:	https://doi.org/10.1186/s12943-025-02532-2
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