A dose-finding study shows terazosin enhanced energy metabolism in neurologically healthy adults

Background Parkinson's disease (PD) is a common neurodegenerative disease lacking treatments that modify progressive neuron loss. Terazosin (TZ) increases activity of the glycolytic enzyme phosphoglycerate kinase 1 and could potentially benefit impaired brain bioenergetics in PD. Preclinical data ar...

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Detalhes bibliográficos

Principais autores:	Jordan L Schultz, Phillip E Gander, Craig D Workman, Laura L Boles Ponto, Stephen Cross, Christopher S Nance, Christopher L Groth, Eric B Taylor, Sarah E Ernst, Jia Xu, Ergun Y Uc, Vincent A Magnotta, Michael J Welsh, Nandakumar S Narayanan
Formato:	Artigo
Idioma:	Inglês
Publicado em:	SAGE Publishing 2025-11-01
coleção:	Journal of Parkinson’s Disease
Acesso em linha:	https://doi.org/10.1177/1877718X251356503
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