Loss of bronchoprotection to Salbutamol during sputum induction with hypertonic saline: implications for asthma therapy

Abstract Background Sputum induction with hypertonic saline in obstructive airway diseases is generally safe. However, saline induces bronchoconstriction in some patients despite pre-medication with Salbutamol. Our objectives were to investigate the predictors of failure of Salbutamol to protect aga...

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Principais autores:	Hongyu Wang, Melanie Kjarsgaard, Terence Ho, John D. Brannan, Parameswaran Nair
Formato:	Artigo
Idioma:	Inglês
Publicado:	BMC 2018-05-01
Series:	Allergy, Asthma & Clinical Immunology
Assuntos:	Hypertonic saline Sputum induction Bronchoconstriction Long-acting beta-agonists Asthma COPD
Acceso en liña:	http://link.springer.com/article/10.1186/s13223-018-0256-7
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