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Identification of the Natural Steroid Sapogenin Diosgenin as a Direct Dual-Specific RORα/γ Inverse Agonist

The steroid sapogenin diosgenin is a well-known natural product with a plethora of described pharmacological activities including the amelioration of T helper 17 (Th17)-driven pathologies. However, the exact underlying mode of action of diosgenin leading to a dampened Th17 response is still largely...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Patrik F. Schwarz, Alexander F. Perhal, Lucia N. Schöberl, Martin M. Kraus, Johannes Kirchmair, Verena M. Dirsch
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: MDPI AG 2022-08-01
Saila:Biomedicines
Gaiak:
Sarrera elektronikoa:https://www.mdpi.com/2227-9059/10/9/2076
Etiketak: Etiketa erantsi
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