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Efflux-Mediated Resistance in <i>Enterobacteriaceae</i>: Recent Advances and Ongoing Challenges to Inhibit Bacterial Efflux Pumps

Efflux is one of the key mechanisms used by Gram-negative bacteria to reduce internal antibiotic concentrations. These active transport systems recognize and expel a wide range of toxic molecules, including antibiotics, thereby contributing to reduced antibiotic susceptibility and allowing the bacte...

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Principais autores: Florent Rouvier, Jean-Michel Brunel, Jean-Marie Pagès, Julia Vergalli
Format: Artigo
Sprog:Inglês
Udgivet: MDPI AG 2025-08-01
Serier:Antibiotics
Fag:
accumulation assay
adjuvants and inhibitors
antibiotics
efflux pumps
fluorometry
Gram-negative bacteria
Online adgang:https://www.mdpi.com/2079-6382/14/8/778
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