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Validation of Pretreatment Methods for the In-Process Quantification of Foot-and-Mouth Disease Vaccine Antigens

Foot-and-mouth disease (FMD), caused by the FMD virus (FMDV), is controlled by vaccine policy in many countries. For vaccine potency, the content of intact virus particles (146S antigens) is critical, and the sucrose density gradient (SDG) fractionation is the gold standard for the quantification of...

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Principais autores: Ah-Young Kim, Sun Young Park, Sang Hyun Park, Jong Sook Jin, Eun-Sol Kim, Jae Young Kim, Jong-Hyeon Park, Young-Joon Ko
Formato: Artigo
Idioma:Inglês
Publicado: MDPI AG 2021-11-01
Series:Vaccines
Assuntos:
foot-and-mouth disease (FMD)
pretreatment
quantification
vaccine antigen
SE-HPLC
Acceso en liña:https://www.mdpi.com/2076-393X/9/11/1361
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