N88S seipin-related seipinopathy is a lipidopathy associated with loss of iron homeostasis
Abstract Background Seipin is a protein encoded by the BSCL2 gene in humans and SEI1 gene in yeast, forming an Endoplasmic Reticulum (ER)-bound homo-oligomer. This oligomer is crucial in targeting ER-lipid droplet (LD) contact sites, facilitating the delivery of triacylglycerol (TG) to nascent LDs....
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| Автори: | , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
BMC
2025-01-01
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| Серія: | Cell Communication and Signaling |
| Предмети: | |
| Онлайн доступ: | https://doi.org/10.1186/s12964-024-02007-9 |
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