Exosomal miR‑301a‑3p of airway epithelial cells regulates macrophage polarization and promotes lung injury via GATA1 pathway in acute respiratory distress syndrome

Abstract Acute respiratory distress syndrome (ARDS) is associated with high morbidity and mortality rates, and macrophage polarization is critical for its pathogenesis. Exosomes are crucial inflammation mediators; however, their role and mechanism in LPS-induced ARDS remain unclear. We investigated...

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Detalhes bibliográficos

Principais autores:	Jing Gao, Xiao Yu, Xiangmei Li, Shilong Zhao, Mengying Yao, Xiaoxiao Lu
Formato:	Artigo
Idioma:	Inglês
Publicado em:	BMC 2026-02-01
coleção:	European Journal of Medical Research
Assuntos:	Acute respiratory distress syndrome Macrophage polarization MicroRNA Inflammatory responses Cell apoptosis
Acesso em linha:	https://doi.org/10.1186/s40001-026-04066-9
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