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Single-cell atlas of human gingiva unveils a NETs-related neutrophil subpopulation regulating periodontal immunity

Introduction: Exaggerated neutrophil recruitment and activation are the major features of pathological alterations in periodontitis, in which neutrophil extracellular traps (NETs) are considered to be responsible for inflammatory periodontal lesions. Despite the critical role of NETs in the developm...

Ausführliche Beschreibung

Gespeichert in:
Hauptverfasser: Wei Qiu, Ruiming Guo, Hongwen Yu, Xiaoxin Chen, Zehao Chen, Dian Ding, Jindou Zhong, Yumeng Yang, Fuchun Fang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Elsevier 2025-06-01
Schriftenreihe:Journal of Advanced Research
Schlagworte:
Periodontitis
Neutrophil extracellular traps
Single-cell RNA sequencing
Gingival fibroblasts
Machine learning
Prediction model
Online-Zugang:http://www.sciencedirect.com/science/article/pii/S2090123224003126
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