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Human NKT10 cells are enriched in cord-derived invariant natural killer T cells and mediate immune-regulation in a xenogeneic graft-versus-host disease model

CD1d-restricted invariant natural killer (iNK) T cells are innate T cells known for their ability to shape adaptive immunity toward inflammation or immune-suppression via the rapid production of Th1-, Th2-, and Th17-type cytokines from corresponding iNKT subsets such as NKT1, NKT2, and NKT17. IL-10-...

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Principais autores: Abel Trujillo-Ocampo, Pamella Borges, Maison Grefe, Martiela Vaz de Freitas, Sung-Eun Lee, Yuan Qi, Jelita Clinton, Dan Li, Hong He, Ling Yu, Arnau Peris-Cuesta, Erik A. Ehli, Qing Ma, Xiaoping Su, Dinler Amaral Antunes, Gheath Al-Atrash, Jeffrey J. Molldrem, Elizabeth J. Shpall, Jin S. Im
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2026-06-01
Serier:Frontiers in Immunology
Fag:
cord-derived iNKT cells
GvHD
immune-regulation
NKT10
transplantation
Online adgang:https://www.frontiersin.org/articles/10.3389/fimmu.2026.1834739/full
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