BIBR1532 combined with radiotherapy induces ferroptosis in NSCLC cells and activates cGAS-STING pathway to promote anti-tumor immunity

Abstract Background Telomerase, by safeguarding damaged telomeres and bolstering DNA damage repair, has the capacity to heighten the radioresistance of tumour cells. Thus, in turn, can compromise the efficacy of radiotherapy (RT) and radioimmunotherapy. Our previous studies have revealed that the hi...

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Prif Awduron:	Yawei Bao, Zhipeng Pan, Luqi Zhao, Jieping Qiu, Jingjing Cheng, Lei Liu, Dong Qian
Fformat:	Artigo
Iaith:	Inglês
Cyhoeddwyd:	BMC 2024-05-01
Cyfres:	Journal of Translational Medicine
Pynciau:	Anti-tumor immunity cGAS-STING pathway Ferroptosis mtDNA release Telomerase inhibitor
Mynediad Ar-lein:	https://doi.org/10.1186/s12967-024-05331-3
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