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Mutated processes predict immune checkpoint inhibitor therapy benefit in metastatic melanoma

Abstract Immune Checkpoint Inhibitor (ICI) therapy has revolutionized treatment for advanced melanoma; however, only a subset of patients benefit from this treatment. Despite considerable efforts, the Tumor Mutation Burden (TMB) is the only FDA-approved biomarker in melanoma. However, the mechanisms...

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Bibliografiska uppgifter
Huvudupphov: Andrew Patterson, Noam Auslander
Materialtyp: Artigo
Språk:Inglês
Utgiven: Nature Portfolio 2022-09-01
Serie:Nature Communications
Länkar:https://doi.org/10.1038/s41467-022-32838-4
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