Repeated α-GalCer Administration Induces a Type 2 Cytokine-Biased iNKT Cell Response and Exacerbates Atopic Skin Inflammation in Vα14^Tg NC/Nga Mice

We have previously shown that Vα14 TCR Tg (Vα14^Tg) NC/Nga (NC) mice contain increased numbers of double-negative (DN) invariant natural killer T (iNKT) cells that protect against spontaneous development of atopic dermatitis (AD). iNKT cells can regulate immune responses by producing vario...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Hyun Jung Park, Tae-Cheol Kim, Yun Hoo Park, Sung Won Lee, Jungmin Jeon, Se-Ho Park, Luc Van Kaer, Seokmann Hong
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2021-11-01
Serie:	Biomedicines
Soggetti:	atopic dermatitis NC/Nga mice iNKT cells Vα14 TCR transgenic mice α-GalCer
Accesso online:	https://www.mdpi.com/2227-9059/9/11/1619
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!