Histological and functional outcomes in a rat model of hemisected spinal cord with sustained VEGF/NT-3 release from tissue-engineered grafts

Microvascular disturbance, excessive inflammation and gliosis are key pathophysiologic changes in relation to functional status following the traumatic spinal cord injury (SCI). Continuous release of vascular endothelial growth factor (VEGF) to the lesion site was proved be able to promote the vascu...

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Autors principals:	Zi-Xing Xu, Li-Qun Zhang, Yi-Nan Zhou, Xue-Min Chen, Wei-Hong Xu
Format:	Artigo
Idioma:	Inglês
Publicat:	Taylor & Francis Group 2020-01-01
Col·lecció:	Artificial Cells, Nanomedicine, and Biotechnology
Matèries:	Spinal cord injury (SCI) vascular endothelial growth factor (VEGF) neurotrophin-3 (NT-3) poly (lactic-co-glycolic acid) (PLGA) nanoparticles angiogenesis neural repair
Accés en línia:	https://www.tandfonline.com/doi/10.1080/21691401.2019.1709860
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