Sialyl-Tn in Cancer: (How) Did We Miss the Target?
Sialyl-Tn antigen (STn) is a short O-glycan containing a sialic acid residue a2,6-linked to GalNAca-O-Ser/Thr. The biosynthesis of STn is mediated by a specific sialyltransferase termed ST6GalNAc I, which competes with O-glycans elongating glycosyltransferases and prevents cancer cells from exhibiti...
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| Hlavní autoři: | , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
MDPI AG
2012-10-01
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| Edice: | Biomolecules |
| Témata: | |
| On-line přístup: | http://www.mdpi.com/2218-273X/2/4/435 |
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