Polydatin and Nicotinamide Rescue the Cellular Phenotype of Mitochondrial Diseases by Mitochondrial Unfolded Protein Response (mtUPR) Activation

Primary mitochondrial diseases result from mutations in nuclear DNA (nDNA) or mitochondrial DNA (mtDNA) genes, encoding proteins crucial for mitochondrial structure or function. Given that few disease-specific therapies are available for mitochondrial diseases, novel treatments to reverse mitochondr...

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Detalles Bibliográficos

Principais autores:	Paula Cilleros-Holgado, David Gómez-Fernández, Rocío Piñero-Pérez, José Manuel Romero Domínguez, Marta Talaverón-Rey, Diana Reche-López, Juan Miguel Suárez-Rivero, Mónica Álvarez-Córdoba, Ana Romero-González, Alejandra López-Cabrera, Marta Castro De Oliveira, Andrés Rodríguez-Sacristan, José Antonio Sánchez-Alcázar
Formato:	Artigo
Idioma:	Inglês
Publicado:	MDPI AG 2024-05-01
Series:	Biomolecules
Assuntos:	mitochondrial diseases <i>GFM1</i> EF-G1 fibroblasts direct reprogramming induced neurons
Acceso en liña:	https://www.mdpi.com/2218-273X/14/5/598
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