Obesity and cervical intraepithelial neoplasia: regulation of mitochondrial energy metabolism via the Kisspeptin/GPR54 signaling pathway

Abstract Background Obesity exacerbates the severity of cervical intraepithelial neoplasia (CIN), potentially through metabolic alterations. This study investigates how the Kisspeptin/GPR54 signaling pathway mediates mitochondrial energy metabolism in obesity-related CIN. Methods A clinical analysis...

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Auteurs principaux:	Jiajia Pan, Yuanyuan Chen, Yan Ye, Peipei Li, Feifei Ni, Haizhen He
Format:	Artigo
Langue:	Inglês
Publié:	BMC 2025-06-01
Collection:	Cancer & Metabolism
Sujets:	Kisspeptin/GPR54 signaling pathway Mitochondrial energy metabolism Cervical intraepithelial neoplasia Obesity Transcriptomics Cervical Cancer cells
Accès en ligne:	https://doi.org/10.1186/s40170-025-00398-y
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