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Human skeletal muscle tissue chip autonomous payload reveals changes in fiber type and metabolic gene expression due to spaceflight

Abstract Microphysiological systems provide the opportunity to model accelerated changes at the human tissue level in the extreme space environment. Spaceflight-induced muscle atrophy experienced by astronauts shares similar physiological changes to muscle wasting in older adults, known as sarcopeni...

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Bibliografiset tiedot
Päätekijät: Maddalena Parafati, Shelby Giza, Tushar S. Shenoy, Jorge A. Mojica-Santiago, Meghan Hopf, Legrand K. Malany, Don Platt, Isabel Moore, Zachary A. Jacobs, Paul Kuehl, Jason Rexroat, Gentry Barnett, Christine E. Schmidt, William T. McLamb, Twyman Clements, Paul M. Coen, Siobhan Malany
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Nature Portfolio 2023-09-01
Sarja:npj Microgravity
Linkit:https://doi.org/10.1038/s41526-023-00322-y
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