Low-dose cryo-electron ptychography of proteins at sub-nanometer resolution

Abstract Cryo-transmission electron microscopy (cryo-EM) of frozen hydrated specimens is an efficient method for the structural analysis of purified biological molecules. However, cryo-EM and cryo-electron tomography are limited by the low signal-to-noise ratio (SNR) of recorded images, making detec...

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Autors principals:	Berk Küçükoğlu, Inayathulla Mohammed, Ricardo C. Guerrero-Ferreira, Stephanie M. Ribet, Georgios Varnavides, Max Leo Leidl, Kelvin Lau, Sergey Nazarov, Alexander Myasnikov, Massimo Kube, Julika Radecke, Carsten Sachse, Knut Müller-Caspary, Colin Ophus, Henning Stahlberg
Format:	Artigo
Idioma:	Inglês
Publicat:	Nature Portfolio 2024-09-01
Col·lecció:	Nature Communications
Accés en línia:	https://doi.org/10.1038/s41467-024-52403-5
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