Peptidomimetics Based on <i>C</i>-Terminus of Blm10 Stimulate Human 20S Proteasome Activity and Promote Degradation of Proteins

Degradation of misfolded, redundant and oxidatively damaged proteins constitutes one of the cellular processes which are influenced by the 20S proteasome. However, its activity is generally thought to decrease with age which leads to the gradual accumulation of abnormal proteins in cells and their s...

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Autori principali:	Katarzyna Cekała, Karolina Trepczyk, Daria Sowik, Przemysław Karpowicz, Artur Giełdoń, Julia Witkowska, Małgorzata Giżyńska, Elżbieta Jankowska, Ewa Wieczerzak
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	MDPI AG 2022-06-01
Serie:	Biomolecules
Soggetti:	proteasome activation 20S neurodegenerative diseases microscale thermophoresis
Accesso online:	https://www.mdpi.com/2218-273X/12/6/777
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