Oncogenic Kras initiates leukemia in hematopoietic stem cells.
How oncogenes modulate the self-renewal properties of cancer-initiating cells is incompletely understood. Activating KRAS and NRAS mutations are among the most common oncogenic lesions detected in human cancer, and occur in myeloproliferative disorders (MPDs) and leukemias. We investigated the effec...
Wedi'i Gadw mewn:
| Prif Awduron: | , , , , , , , , |
|---|---|
| Fformat: | Artigo |
| Iaith: | Inglês |
| Cyhoeddwyd: |
Public Library of Science (PLoS)
2009-03-01
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| Cyfres: | PLoS Biology |
| Mynediad Ar-lein: | http://europepmc.org/articles/PMC2656550?pdf=render |
| Tagiau: |
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